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Circulation of bla KPC-3 -Carrying IncX3 Plasmids among Citrobacter freundii Isolates in an Italian Hospital
Author(s) -
Carolina Venditti,
D. Fortini,
Laura Villa,
Antonella Vulcano,
Silvia D’Arezzo,
Alessandro Capone,
Nicola Petrosillo,
Carla Nisii,
Alessandra Carattoli,
Antonino Di
Publication year - 2017
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.00505-17
Subject(s) - citrobacter freundii , plasmid , citrobacter , microbiology and biotechnology , enterobacteriaceae , biology , klebsiella pneumoniae , gene , escherichia coli , genetics
Colonizations due to carbapenem-resistantEnterobacteriaceae (CRE) are a source of antimicrobial resistance transmission in health care settings. ElevenCitrobacter freundii strains producing KPC-3 carbapenemase were isolated from rectal swabs during a 3-year surveillance program.bla KPC-3 -carrying plasmids were found to belong to the IncX3 group in 9 of the 11 strains, and complete nucleotide sequences were obtained for 2 of them. Our results highlight the possible role ofC. freundii as reservoir of resistance genes.

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