Plasmid with Colistin Resistance Gene mcr-1 in Extended-Spectrum-β-Lactamase-Producing Escherichia coli Strains Isolated from Pig Slurry in Estonia | Zendy

Age Brauer | Zendy; Kaidi Telling | Zendy; Mailis Laht | Zendy; Piret Kalmus | Zendy; Irja Lutsar | Zendy; Maido Remm | Zendy; Veljo Kisand | Zendy; Tanel Tenson | Zendy

Open Access

Plasmid with Colistin Resistance Gene mcr-1 in Extended-Spectrum-β-Lactamase-Producing Escherichia coli Strains Isolated from Pig Slurry in Estonia

Author(s) -

Age Brauer,

Kaidi Telling,

Mailis Laht,

Piret Kalmus,

Irja Lutsar,

Maido Remm,

Veljo Kisand,

Tanel Tenson

Publication year - 2016

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00443-16

Subject(s) - mcr 1 , plasmid , escherichia coli , biology , microbiology and biotechnology , colistin , gene , operon , horizontal gene transfer , enterobacteriaceae , plasmid preparation , genetics , antibiotics , phylogenetics , pbr322

A plasmid carrying the colistin resistance genemcr-1 was isolated from a pig slurry sample in Estonia. The gene was present on a 33,311-bp plasmid of the IncX4 group.mcr-1 is the only antibiotic resistance gene on the plasmid, with the other genes mainly coding for proteins involved in conjugative DNA transfer (taxA ,taxB ,taxC ,trbM , and thepilX operon). The plasmid pESTMCR was present in three phylogenetically very differentEscherichia coli strains, suggesting that it has high potential for horizontal transfer.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research