High Prevalence of Metallo-β-Lactamase and 16S rRNA Methylase Coproduction among Imipenem-Resistant Pseudomonas aeruginosa Isolates in Brazil | Zendy

Yohei Doi | Zendy; A C R Ghilardi | Zendy; Jennifer Adams | Zendy; Doroti de Oliveira Garcia | Zendy; David L. Paterson | Zendy

Open Access

High Prevalence of Metallo-β-Lactamase and 16S rRNA Methylase Coproduction among Imipenem-Resistant Pseudomonas aeruginosa Isolates in Brazil

Author(s) -

Yohei Doi,

A C R Ghilardi,

Jennifer Adams,

Doroti de Oliveira Garcia,

David L. Paterson

Publication year - 2007

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00443-07

Subject(s) - pseudomonas aeruginosa , imipenem , microbiology and biotechnology , 16s ribosomal rna , coproduction , biology , ribosomal rna , pseudomonas , bacteria , genetics , gene , public relations , political science

Rates of metallo-beta-lactamase and 16S rRNA methylase production were investigated in 51 imipenem-resistant Pseudomonas aeruginosa clinical isolates collected from hospitals in São Paulo, Brazil. Of them, 57% and 75% produced SPM-1 and RmtD, respectively. Of note, 51% produced both enzymes, suggesting that their coproduction is already common in this geographic area.

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