In Vitro Evaluation of the Activities of Telavancin, Cefazolin, and Vancomycin against Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus in Peritoneal Dialysate | Zendy

Frances L. Clouse | Zendy; Laurie B. Hovde | Zendy; John C. Rotschafer | Zendy

Open Access

In Vitro Evaluation of the Activities of Telavancin, Cefazolin, and Vancomycin against Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus in Peritoneal Dialysate

Author(s) -

Frances L. Clouse,

Laurie B. Hovde,

John C. Rotschafer

Publication year - 2007

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00435-07

Subject(s) - cefazolin , vancomycin , microbiology and biotechnology , staphylococcus aureus , methicillin resistant staphylococcus aureus , staphylococcus , micrococcaceae , medicine , antibiotics , antibacterial agent , biology , bacteria , genetics

This study compared the ability of telavancin to the ability of cefazolin and vancomycin to eliminate staphylococci from peritoneal dialysis fluid by using a static in vitro model to simulate the conditions of peritoneal dialysis. The results showed that telavancin exhibited statistically significantly better kill (P < 0.05) against both methicillin-susceptible and methicillin-resistant Staphylococcus aureus.

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