IS Ecp1 -Mediated Transposition of qnrB -Like Gene in Escherichia coli | Zendy

Vincent Cattoir | Zendy; Patrice Nordmann | Zendy; Jesús Silva-Sánchez | Zendy; Paula Espinal | Zendy; Laurent Poirel | Zendy

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IS Ecp1 -Mediated Transposition of qnrB -Like Gene in Escherichia coli

Author(s) -

Vincent Cattoir,

Patrice Nordmann,

Jesús Silva-Sánchez,

Paula Espinal,

Laurent Poirel

Publication year - 2008

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00349-08

Subject(s) - transposition (logic) , escherichia coli , plasmid , gene , transposable element , biology , insertion sequence , genetics , genome , philosophy , linguistics

A novel QnrB-like plasmid-mediated resistance determinant, QnrB19, was identified from anEscherichia coli clinical isolate from Colombia. Its gene was associated with an ISEcp1 -like insertion element that did not act as a promoter for its expression. Using an in vitro model of transposition, we showed that the ISEcp1 -like element was able to mobilize theqnrB19 gene.

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