Germicidal Activity against Carbapenem/Colistin-Resistant Enterobacteriaceae Using a Quantitative Carrier Test Method | Zendy

Hajime Kanamori | Zendy; William A. Rutala | Zendy; Maria F. Gergen | Zendy; Emily Sickbert-Bennett | Zendy; David J. Weber | Zendy

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Germicidal Activity against Carbapenem/Colistin-Resistant Enterobacteriaceae Using a Quantitative Carrier Test Method

Author(s) -

Hajime Kanamori,

William A. Rutala,

Maria F. Gergen,

Emily Sickbert-Bennett,

David J. Weber

Publication year - 2018

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00318-18

Subject(s) - colistin , enterobacteriaceae , carbapenem resistant enterobacteriaceae , carbapenem , microbiology and biotechnology , enterobacteriaceae infections , polymyxin , antibiotics , medicine , biology , escherichia coli , biochemistry , gene

Susceptibility to germicides for carbapenem/colistin-resistant Enterobacteriaceae is poorly described. We investigated the efficacy of multiple germicides against these emerging antibiotic-resistant pathogens using the disc-based quantitative carrier test method that can produce results more similar to those encountered in health care settings than a suspension test. Our study results demonstrated that germicides commonly used in health care facilities likely will be effective against carbapenem/colistin-resistant Enterobacteriaceae when used appropriately in health care facilities.

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