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Antifungal Prophylaxis Is Effective against Murine Invasive Pulmonary Aspergillosis
Author(s) -
Günter Rieg,
Brad Spellberg,
Julie Schwartz,
Yue Fu,
John E. Edwards,
Donald C. Sheppard,
Ashraf S. Ibrahim
Publication year - 2006
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.00299-06
Subject(s) - antifungal , aspergillosis , medicine , echinocandins , pulmonary aspergillosis , intensive care medicine , mycosis , voriconazole , immunology , caspofungin , dermatology
Antifungal prophylaxis for patients at high risk for aspergillosis is appealing due to the high morbidity and mortality of aspergillosis despite antifungal therapy ([1][1]-[3][2]). While voriconazole is a logical option, reports of breakthrough mucormycosis are a cause for concern ([5][3]). To

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