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lacZ fusion strains were constructed using the promoters of five cell wall stress stimulon genes: pbp2, tcaA, vraSR, sgtB, and lytR. All fusion strains were induced only in the presence of cell wall-active antibiotics, suggesting the potential of these strains for use in high-throughput screening for new cell wall-active agents.

antimicrobial agents and chemotherapy

<i>Staphylococcus aureus</i> Cell Wall Stress Stimulon Gene <i>-lacZ</i> Fusion Strains: Potential for Use in Screening for Cell Wall-Active Antimicrobials

Staphylococcus aureus Cell Wall Stress Stimulon Gene -lacZ Fusion Strains: Potential for Use in Screening for Cell Wall-Active Antimicrobials