Synergistic Effect of Colistin Combined with PFK-158 against Colistin-Resistant Enterobacteriaceae
Author(s) -
Youwen Zhang,
Xiukun Wang,
Xue Li,
Limin Dong,
Xinxin Hu,
Tongying Nie,
Yun Lu,
Xi Lü,
Jing Pang,
Guoqing Li,
Xinyi Yang,
Congran Li,
Xuefu You
Publication year - 2019
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.00271-19
Subject(s) - colistin , klebsiella pneumoniae , enterobacteriaceae , enterobacter cloacae , microbiology and biotechnology , escherichia coli , mcr 1 , in vivo , pharmacology , biology , antimicrobial , medicine , biochemistry , gene
As increasing numbers of colistin-resistant bacteria emerge, new therapies are urgently needed to treat infections caused by these pathogens. The discovery of new combination therapies is one important way to solve such problems.
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