A Plasmid Bearing the bla CTX-M-15 Gene and Phage P1-Like Sequences from a Sequence Type 11 Klebsiella pneumoniae Isolate | Zendy

Juyoun Shin | Zendy; Kwan Soo Ko | Zendy

Open Access

A Plasmid Bearing the bla _CTX-M-15 Gene and Phage P1-Like Sequences from a Sequence Type 11 Klebsiella pneumoniae Isolate

Author(s) -

Juyoun Shin,

Kwan Soo Ko

Publication year - 2015

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00265-15

Subject(s) - plasmid , klebsiella pneumoniae , biology , escherichia coli , microbiology and biotechnology , gene , enterobacteriaceae , genetics

Plasmid pKP12226 was extracted and analyzed from a CTX-M-15-producing Klebsiella pneumoniae sequence type 11 (ST11) isolate collected in South Korea. The plasmid represents chimeric characteristics consisting of a pIP1206-like backbone and lysogenized phage P1-like sequences. It bears a resistance region that includes resistance genes to several antibiotics and is different from previously characterized plasmids from South Korea bearing blaCTX-M-15. It may have resulted from recombination between an Escherichia coli plasmid backbone, a blaCTX-M-15-bearing resistance region, and lysogenized phage P1-like sequences.

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