Open AccessFirst Report of Plasmid-Mediated Quinolone Resistance Determinant qnrS1 in an Escherichia coli Strain of Animal Origin in Italy
Author(s) -
Marina Cerquetti,
Aurora García-Fernández,
Maria Giufrè,
Daniela Fortini,
Marisa Accogli,
Caterina Graziani,
Ida Luzzi,
Alfredo Caprioli,
Alessandra Carattoli
Publication year - 2009
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.00239-09
Subject(s) - salmonella enterica , plasmid , escherichia coli , transposable element , microbiology and biotechnology , biology , salmonella , strain (injury) , serotype , ciprofloxacin , enterobacteriaceae , escherichia , genetics , gene , bacteria , mutant , antibiotics , anatomy
AqnrS1 -positive strain ofEscherichia coli was detected among 73 poultry isolates showing ciprofloxacin MICs of ≥0.125 μg/ml. TheqnrS1 gene was associated with a Tn3 -like transposon, as previously described to occur in aSalmonella enterica serovar Infantis strain of animal origin, but the plasmid scaffold carrying this element resembled that of a plasmid previously identified inSalmonella enterica serovar Dublin. These elements suggest genetic exchanges amongSalmonella andE. coli and a potential animal reservoir for theqnr genes.