Distribution of Staphylococcal Cassette Chromosome (SCC) mec Element Types in Fusidic Acid-Resistant Staphylococcus epidermidis and Identification of a Novel SCC 7684 Element | Zendy

Hsiao-Jan Chen | Zendy; Yu-Tzu Lin | Zendy; WeiChun Hung | Zendy; JuiChang Tsai | Zendy; PoRen Hsueh | Zendy; LeeJene Teng | Zendy

Open Access

Distribution of Staphylococcal Cassette Chromosome (SCC) mec Element Types in Fusidic Acid-Resistant Staphylococcus epidermidis and Identification of a Novel SCC 7684 Element

Author(s) -

Hsiao-Jan Chen,

Yu-Tzu Lin,

WeiChun Hung,

JuiChang Tsai,

PoRen Hsueh,

LeeJene Teng

Publication year - 2016

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00231-16

Subject(s) - sccmec , staphylococcus epidermidis , fusidic acid , microbiology and biotechnology , biology , staphylococcus aureus , staphylococcal infections , genetics , methicillin resistant staphylococcus aureus , bacteria

We analyzed the staphylococcal cassette chromosomemec (SCCmec ) types of 143 fusidic acid- and methicillin-resistantStaphylococcus epidermidis isolates. The most frequent SCCmec type was SCCmec III/SCCHg (53%), followed by SCCmec IV (29%). Clonal spreading of SCCmec III/SCCHg strains contributed to the increased prevalence of SCCmec III. A novel non-mec SCC structure, SCC7684 , adjacent to SCCmec III, which carries a newccrC allotype (ccrC3 allele 1) and contains heavy metal resistance genes, was identified in 14 isolates.

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