Sertaconazole Nitrate Shows Fungicidal and Fungistatic Activities against Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum, Causative Agents of Tinea Pedis | Zendy

Alfonso Javier CarrilloMuñoz | Zendy; Cristina TurTur | Zendy; Délia Cárdenes | Zendy; D. Estivill | Zendy; Gustavo Giusiano | Zendy

Open Access

Sertaconazole Nitrate Shows Fungicidal and Fungistatic Activities against Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum, Causative Agents of Tinea Pedis

Author(s) -

Alfonso Javier CarrilloMuñoz,

Cristina TurTur,

Délia Cárdenes,

D. Estivill,

Gustavo Giusiano

Publication year - 2011

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00219-11

Subject(s) - epidermophyton floccosum , trichophyton , trichophyton rubrum , fungicide , microsporum , microbiology and biotechnology , tinea capitis , biology , dermatophyte , antifungal , botany

The fungistatic and fungicidal activities of sertaconazole against dermatophytes were evaluated by testing 150 clinical isolates of causative agents of tinea pedis, Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum. The overall geometric means for fungistatic and fungicidal activities of sertaconazole against these isolates were 0.26 and 2.26 μg/ml, respectively, although values were higher for T. mentagrophytes than for the others. This is the first comprehensive demonstration of the fungicidal activity of sertaconazole against dermatophytes.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research