Open AccessIn Vitro Activity of Anidulafungin against Candida albicans Biofilms
Author(s) -
Mark Jacobson,
Kerryl E. Piper,
Gary Nguyen,
James M. Steckelberg,
Robin Patel
Publication year - 2008
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.00211-08
Subject(s) - anidulafungin , candida albicans , microbiology and biotechnology , minimum inhibitory concentration , biology , in vitro , antimicrobial , antifungal , fluconazole , micafungin , biochemistry
We tested the activity of anidulafungin against 30Candida albicans isolates. The planktonic MICs for 50 and 90% of the isolates tested (MIC50 and MIC90 ) were ≤0.03 and 0.125 μg/ml, respectively (MIC range, ≤0.03 to 2 μg/ml). The sessile MIC50 and MIC90 were ≤0.03 and ≤0.03 μg/ml, respectively (MIC range, ≤0.03 to >16 μg/ml).