In Vitro Activity of Anidulafungin against Candida albicans Biofilms | Zendy

Melissa Jacobson | Zendy; Kerryl E. Piper | Zendy; Gary Nguyen | Zendy; James M. Steckelberg | Zendy; Robin Patel | Zendy

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In Vitro Activity of Anidulafungin against Candida albicans Biofilms

Author(s) -

Melissa Jacobson,

Kerryl E. Piper,

Gary Nguyen,

James M. Steckelberg,

Robin Patel

Publication year - 2008

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00211-08

Subject(s) - anidulafungin , candida albicans , microbiology and biotechnology , minimum inhibitory concentration , biology , in vitro , antimicrobial , antifungal , fluconazole , micafungin , biochemistry

We tested the activity of anidulafungin against 30Candida albicans isolates. The planktonic MICs for 50 and 90% of the isolates tested (MIC50 and MIC90 ) were ≤0.03 and 0.125 μg/ml, respectively (MIC range, ≤0.03 to 2 μg/ml). The sessile MIC50 and MIC90 were ≤0.03 and ≤0.03 μg/ml, respectively (MIC range, ≤0.03 to >16 μg/ml).

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