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To guide the timely selection of antibiotic combinations against carbapenem-resistant Gram-negative bacteria (CR-GNB), anin vitro test with a short turnaround time is essential. We developed anin vitro ATP bioluminescence assay to determine effective antibiotic combinations against CR-GNB within 6 h.

Rapid Antibiotic Combination Testing for Carbapenem-Resistant Gram-Negative Bacteria within Six Hours Using ATP Bioluminescence