Open AccessFirst Report of the Multidrug Resistance Gene cfr and the Phenicol Resistance Gene fexA in a Bacillus Strain from Swine Feces
Author(s) -
Lei Dai,
Congming Wu,
Minggui Wang,
Yang Wang,
Yu Wang,
SiYang Huang,
Lining Xia,
Beibei Li,
Jianzhong Shen
Publication year - 2010
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.00169-10
Subject(s) - gene , biology , plasmid , multiple drug resistance , microbiology and biotechnology , strain (injury) , genetics , drug resistance , anatomy
A multidrug resistance gene, cfr, and a phenicol resistance gene, fexA, were detected in a Bacillus strain, BS-01, isolated from swine feces. The cfr gene was carried on a novel 16.5-kb plasmid, designated pBS-01. A complete Tn917 structure, which harbors the macrolide-lincosamide-streptogramin B resistance gene erm(B), was located downstream of the cfr gene. The fexA gene was discovered in the chromosomal DNA of the BS-01 strain and identified in a Tn558 variant.