In Vitro Activities of 10 Combinations of Antifungal Agents against the Multiresistant Pathogen Scopulariopsis brevicaulis | Zendy

Manuel CuencaEstrella | Zendy; Alicia GómezLópez | Zendy; María José Buitrago | Zendy; Emilia Mellado | Zendy; Guillermo GarcíaEffrón | Zendy; Juan L. Rodrı́guez-Tudela | Zendy

Open Access

In Vitro Activities of 10 Combinations of Antifungal Agents against the Multiresistant Pathogen Scopulariopsis brevicaulis

Author(s) -

Manuel CuencaEstrella,

Alicia GómezLópez,

María José Buitrago,

Emilia Mellado,

Guillermo GarcíaEffrón,

Juan L. Rodrı́guez-Tudela

Publication year - 2006

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00162-06

Subject(s) - posaconazole , caspofungin , terbinafine , checkerboard , microbiology and biotechnology , antifungal , biology , voriconazole , pathogen , amphotericin b , itraconazole

The activities of 10 combinations of antifungal agents against 25 clinical isolates of Scopulariopsis brevicaulis were tested by the checkerboard technique. An average indifferent effect was detected for all combinations. Synergy was observed for some isolates and combinations, particularly with posaconazole-terbinafine (68% of strains), amphotericin B-caspofungin (60%), and posaconazole-caspofungin (48%).

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