In Vivo Therapeutic Effect of Gatifloxacin on BALB/c Mice Infected with Nocardia brasiliensis | Zendy

Alejandra Daw-Garza | Zendy; Oliverio Welsh | Zendy; Salvador SaidFernández | Zendy; Héctor Gerardo Lozano-Garza | Zendy; Noemí Waksman de Torres | Zendy; Norma Cavazos-Rocha | Zendy; Jorge OcampoCandiani | Zendy; Lucio VeraCabrera | Zendy

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In Vivo Therapeutic Effect of Gatifloxacin on BALB/c Mice Infected with Nocardia brasiliensis

Author(s) -

Alejandra Daw-Garza,

Oliverio Welsh,

Salvador SaidFernández,

Héctor Gerardo Lozano-Garza,

Noemí Waksman de Torres,

Norma Cavazos-Rocha,

Jorge OcampoCandiani,

Lucio VeraCabrera

Publication year - 2008

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00148-08

Subject(s) - gatifloxacin , linezolid , balb/c , in vivo , nocardia brasiliensis , microbiology and biotechnology , nocardia , pharmacology , medicine , biology , antibiotics , immunology , bacteria , nocardiosis , staphylococcus aureus , levofloxacin , genetics , immune system , vancomycin

In the present work, we evaluated the effect of gatifloxacin on the evolution of experimental murine infection withNocardia brasiliensis using linezolid as a control. Gatifloxacin was injected subcutaneously at 100 mg/kg body weight every 8 h for 4 weeks. This compound was equally as efficient as linezolid in reducing the production of lesions.

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