Emergence of Fluoroquinolone Resistance in Group B Streptococcal Isolates in Taiwan
Author(s) -
HsiuMei Wu,
Rajendra Prasad Janapatla,
Yueh-Ren Ho,
KueiHsiang Hung,
Chi-Wen Wu,
Jing-Jou Yan,
Jiunn-Jong Wu
Publication year - 2008
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.00035-08
Subject(s) - levofloxacin , microbiology and biotechnology , streptococcaceae , biology , group a , ofloxacin , group b , drug resistance , antibacterial agent , antibiotics , medicine , ciprofloxacin
Of 1,994 group B streptococcal isolates collected, 26 (1.3%) of the isolates were resistant to levofloxacin, and cross-resistance to other fluoroquinolones was observed. The emergence and prevalence of high-level fluoroquinolone resistance in genetically unrelated isolates were linked to the presence of gyrA, parC, and parE triple mutations in each isolate.
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