Etest Cannot Be Recommended for In Vitro Susceptibility Testing of Mucorales | Zendy

Rita Caramalho | Zendy; Elisabeth Maurer | Zendy; Ulrike Binder | Zendy; Ricardo Araújo | Zendy; Somayeh Dolatabadi | Zendy; Cornelia LassFlörl | Zendy; Michaela Lackner | Zendy

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Etest Cannot Be Recommended for In Vitro Susceptibility Testing of Mucorales

Author(s) -

Rita Caramalho,

Elisabeth Maurer,

Ulrike Binder,

Ricardo Araújo,

Somayeh Dolatabadi,

Cornelia LassFlörl,

Michaela Lackner

Publication year - 2015

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00004-15

Subject(s) - mucorales , etest , in vitro , medicine , biology , microbiology and biotechnology , genetics , pathology , mucormycosis , antibiotics

Amphotericin B and posaconazole susceptibility patterns were determined for the most prevalent Mucorales, following EUCAST (European Committee on Antimicrobial Susceptibility Testing) broth microdilution guidelines. In parallel, Etest was performed and evaluated against EUCAST. The overall agreement of MICs gained with Etest and EUCAST was 75.1%; therefore, Etest cannot be recommended for antifungal susceptibility testing of Mucorales. Amphotericin B was the most active drug against Mucorales speciesin vitro , while the activities of posaconazole were more restricted.

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