Reducing Mortality in Salmonella enterica Serovar Typhimurium-Infected Mice with a Tripeptidic Serum Fraction | Zendy

Todd A. Parker | Zendy; Kenneth O. Willeford | Zendy; Suzanne L. Parker | Zendy; Karyl K. Buddington | Zendy

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Reducing Mortality in Salmonella enterica Serovar Typhimurium-Infected Mice with a Tripeptidic Serum Fraction

Author(s) -

Todd A. Parker,

Kenneth O. Willeford,

Suzanne L. Parker,

Karyl K. Buddington

Publication year - 2002

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac;46.6.1971-1973.2002

Subject(s) - immunostimulant , salmonella enterica , salmonella , serotype , microbiology and biotechnology , medicine , biology , enterobacteriaceae , immunology , virology , bacteria , escherichia coli , immune system , genetics , biochemistry , gene

Salmonellosis-induced mortality in female Swiss Webster mice decreased significantly when tripeptidic immunostimulant (TPI) was administered prophylactically. Prophylactic benefits developed in a dose-dependent manner wherein 15 mg of TPI given 1 day before challenge reduced mortality by 70%.

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