TCR sequencing facilitates diagnosis and identifies mature T cells as the cell of origin in CTCL | Zendy

Ilan R. Kirsch | Zendy; Rei Watanabe | Zendy; John T. O’Malley | Zendy; David Williamson | Zendy; Laura-Louise Scott | Zendy; Christopher P. Elco | Zendy; Jessica E. Teague | Zendy; Ahmed Gehad | Zendy; Elizabeth L. Lowry | Zendy; Nicole R. LeBoeuf | Zendy; James G. Krueger | Zendy; Harlan Robins | Zendy; Thomas S. Kupper | Zendy; Rachael A. Clark | Zendy

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TCR sequencing facilitates diagnosis and identifies mature T cells as the cell of origin in CTCL

Author(s) -

Ilan R. Kirsch,

Rei Watanabe,

John T. O’Malley,

David Williamson,

Laura-Louise Scott,

Christopher P. Elco,

Jessica E. Teague,

Ahmed Gehad,

Elizabeth L. Lowry,

Nicole R. LeBoeuf,

James G. Krueger,

Harlan Robins,

Thomas S. Kupper,

Rachael A. Clark

Publication year - 2015

Publication title -

science translational medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.819

H-Index - 216

eISSN - 1946-6242

pISSN - 1946-6234

DOI - 10.1126/scitranslmed.aaa9122

Subject(s) - mycosis fungoides , cutaneous t cell lymphoma , t cell receptor , t cell , clone (java method) , lymphoma , malignancy , peripheral t cell lymphoma , medicine , pathology , biology , immunology , dermatology , gene , immune system , biochemistry

High-throughput TCR sequencing can accurately diagnose and discriminate CTCL cells in skin.

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