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Targeting phosphatase-dependent proteoglycan switch for rheumatoid arthritis therapy
Author(s) -
Karen M. Doody,
Stephanie M. Stanford,
Cristiano Sacchetti,
Mattias N. D. Svensson,
C.H. Coles,
Nikolaos Mitakidis,
William B. Kiosses,
Beatrix Bartók,
Camille Fos,
Esther Cory,
Robert L. Sah,
Ru LiuBryan,
David L. Boyle,
Heather A. Arnett,
Tomas Mustelin,
Maripat Corr,
Jeffrey D. Esko,
Michel L. Tremblay,
Gary S. Firestein,
A.R. Aricescu,
Nunzio Bottini
Publication year - 2015
Publication title -
science translational medicine
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 6.819
H-Index - 216
eISSN - 1946-6242
pISSN - 1946-6234
DOI - 10.1126/scitranslmed.aaa4616
Subject(s) - rheumatoid arthritis , proteoglycan , medicine , arthritis , fibroblast , phosphatase , alkaline phosphatase , cancer research , immunology , biology , enzyme , cartilage , biochemistry , anatomy , in vitro
Targeting joint-lining fibroblast-like synoviocytes reduces the severity of arthritis.

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