Open AccessTumor cells, but not endothelial cells, mediate eradication of primary sarcomas by stereotactic body radiation therapy
Author(s) -
Everett J. Moding,
Katherine D. Castle,
Bradford A. Perez,
Patrick Oh,
Hooney Min,
Hannah Norris,
Yan Ma,
Diana M. Cardona,
ChangLung Lee,
David G. Kirsch
Publication year - 2015
Publication title -
science translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.819
H-Index - 216
eISSN - 1946-6242
pISSN - 1946-6234
DOI - 10.1126/scitranslmed.aaa4214
Subject(s) - cancer research , sarcoma , radiation therapy , genetic enhancement , radiosensitivity , medicine , endothelial stem cell , bystander effect , biology , pathology , immunology , gene , genetics , in vitro
Tumor cells, rather than endothelial cells, are critical targets that regulate primary sarcoma eradication by radiation therapy.
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