The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension | Zendy

Masato Morikawa | Zendy; Yoshihide Mitani | Zendy; Katarina Holmborn | Zendy; Taichi Kato | Zendy; Daizo Koinuma | Zendy; Junko Maruyama | Zendy; Eleftheria Vasilaki | Zendy; Hirofumi Sawada | Zendy; Mai Kobayashi | Zendy; Takayuki Ozawa | Zendy; Yasuyuki Morishita | Zendy; Yasumasa Bessho | Zendy; Shingo Maeda | Zendy; Johan Ledin | Zendy; Hiroyuki Aburatani | Zendy; Ryoichiro Kageyama | Zendy; Kazuo Maruyama | Zendy; CarlHenrik Heldin | Zendy; Kohei Miyazono | Zendy

Open Access

The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension

Author(s) -

Masato Morikawa,

Yoshihide Mitani,

Katarina Holmborn,

Taichi Kato,

Daizo Koinuma,

Junko Maruyama,

Eleftheria Vasilaki,

Hirofumi Sawada,

Mai Kobayashi,

Takayuki Ozawa,

Yasuyuki Morishita,

Yasumasa Bessho,

Shingo Maeda,

Johan Ledin,

Hiroyuki Aburatani,

Ryoichiro Kageyama,

Kazuo Maruyama,

CarlHenrik Heldin,

Kohei Miyazono

Publication year - 2019

Publication title -

science signaling

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.659

H-Index - 154

eISSN - 1937-9145

pISSN - 1945-0877

DOI - 10.1126/scisignal.aay4430

Subject(s) - smad , pulmonary hypertension , transcription factor , medicine , bone morphogenetic protein receptor , transforming growth factor , microbiology and biotechnology , chemistry , cardiology , biology , bone morphogenetic protein , biochemistry , gene

BMP signaling induces a transcription factor that may block pulmonary arterial hypertension from developing.

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