L-type Ca 2+ channel–mediated Ca 2+ influx adjusts neuronal mitochondrial function to physiological and pathophysiological conditions
Author(s) -
Matej Hoťka,
Michal Cagalinec,
Karlheinz Hilber,
Livia C. Hool,
Stefan Boehm,
Helmut Kubista
Publication year - 2020
Publication title -
science signaling
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.659
H-Index - 154
eISSN - 1937-9145
pISSN - 1945-0877
DOI - 10.1126/scisignal.aaw6923
Subject(s) - mitochondrion , microbiology and biotechnology , extracellular , biophysics , uniporter , bicuculline , chemistry , biology , neuroscience , biochemistry , gabaa receptor , cytosol , receptor , enzyme
L-type Ca2+ channel activity confers neuroprotection by inducing the ATP synthase to operate in reverse mode.
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