Open AccessRegulated proteolysis of p62/SQSTM1 enables differential control of autophagy and nutrient sensing
Author(s) -
Julia SanchezGarrido,
Vanessa SanchoShimizu,
Avinash R. Shenoy
Publication year - 2018
Publication title -
science signaling
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.659
H-Index - 154
eISSN - 1937-9145
pISSN - 1945-0877
DOI - 10.1126/scisignal.aat6903
Subject(s) - autophagy , proteolysis , microbiology and biotechnology , nutrient , nutrient sensing , ubiquitin , biology , chemistry , apoptosis , biochemistry , signal transduction , ecology , gene , enzyme
A p62 fragment generated by caspase-8 regulates responses to nutrient availability, rather than autophagy.
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