Open AccessH 2 S production by reactive oxygen species in the carotid body triggers hypertension in a rodent model of sleep apnea
Author(s) -
Guoxiang Yuan,
Yingjie Peng,
Shakil A. Khan,
Jayasri Nanduri,
Amritha T Singh,
Chirag Vasavda,
Gregg L. Semenza,
Ganesh K. Kumar,
Solomon H. Snyder,
Nanduri R. Prabhakar
Publication year - 2016
Publication title -
science signaling
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.659
H-Index - 154
eISSN - 1937-9145
pISSN - 1945-0877
DOI - 10.1126/scisignal.aaf3204
Subject(s) - carotid body , intermittent hypoxia , hypoxia (environmental) , reactive oxygen species , sleep apnea , endocrinology , medicine , apnea , obstructive sleep apnea , reflex , chemistry , oxygen , biochemistry , organic chemistry , stimulation
Suppressing hydrogen sulfide production in the carotid body may prevent the hypertension associated with sleep apnea.
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