Open AccessComprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use
Author(s) -
Jing Sun,
Ning Li,
Kyu-Seon Oh,
Bhaskar Dutta,
Sharat J. Vayttaden,
Bin Lin,
Thomas S. Ebert,
Dominic De Nardo,
Joie Davis,
Rustam Bagirzadeh,
Nicolas Lounsbury,
Chandrashekhar Pasare,
Eicke Latz,
Veit Hornung,
Iain D. C. Fraser
Publication year - 2016
Publication title -
science signaling
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.659
H-Index - 154
eISSN - 1937-9145
pISSN - 1945-0877
DOI - 10.1126/scisignal.aab2191
Subject(s) - signal transduction , biology , rna interference , microbiology and biotechnology , toll like receptor , receptor , computational biology , gene , innate immune system , genetics , rna
Comparative analysis of mouse and human macrophages reveals conserved and species-specific use of Toll-like receptor signaling components.
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