Open AccessSurvivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasion
Author(s) -
Dayana B. Rivadeneira,
M. Cecilia Caino,
Jae Ho Seo,
Alessia Angelin,
Douglas C. Wallace,
Lucia R. Languino,
Dario C. Altieri
Publication year - 2015
Publication title -
science signaling
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.659
H-Index - 154
eISSN - 1937-9145
pISSN - 1945-0877
DOI - 10.1126/scisignal.aab1624
Subject(s) - survivin , mitochondrion , microbiology and biotechnology , membrane ruffling , oxidative phosphorylation , biology , apoptosis , cell , cancer research , metastasis , cancer cell , cytoskeleton , cancer , biochemistry , genetics
Targeting the protein survivin could reduce metastasis by preventing energy production needed for cancer cell motility.
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