Open AccessProtein phosphatase 2A regulatory subunit B56α limits phosphatase activity in the heart
Author(s) -
Sean C. Little,
Jerry Curran,
Michael Makara,
Crystal F. Kline,
Hsiang-Ting Ho,
Zhaobin Xu,
Xiangqiong Wu,
Iuliia Polina,
Hassan Musa,
Allison M. Meadows,
Cynthia A. Carnes,
Brandon J. Biesiadecki,
Jonathan P. Davis,
Noah Weisleder,
Sándor Györke,
Xander H.T. Wehrens,
Thomas J. Hund,
Peter J. Mohler
Publication year - 2015
Publication title -
science signaling
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.659
H-Index - 154
eISSN - 1937-9145
pISSN - 1945-0877
DOI - 10.1126/scisignal.aaa5876
Subject(s) - protein phosphatase 2 , phosphatase , phosphorylation , protein subunit , dephosphorylation , cav1.2 , microbiology and biotechnology , serine , biology , intracellular , endocrinology , medicine , chemistry , biochemistry , gene
Targeting a regulatory subunit in the phosphatase PP2A could limit arrhythmias caused by excessive adrenergic stimulation.
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