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Focus Issue: Signaling Architecture from Domains to Complexes
Author(s) -
Wei Wong,
Nancy R. Gough
Publication year - 2012
Publication title -
science signaling
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.659
H-Index - 154
eISSN - 1937-9145
pISSN - 1945-0877
DOI - 10.1126/scisignal.2003235
Subject(s) - focus (optics) , signal transduction , microbiology and biotechnology , computational biology , signaling proteins , biology , neuroscience , chemistry , physics , optics
Science Signaling concludes a series on structural biology, which has focused on the use of structural approaches to understand signal transduction. Articles in this issue highlight the importance of the helical domain in Gα proteins, discuss how linear peptide motifs are recognized by a protein domain, and describe the assembly of macromolecular complexes upon activation of Toll-like and interleukin-1 receptors.

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