Open AccessSeverely ill patients with COVID-19 display impaired exhaustion features in SARS-CoV-2–reactive CD8 + T cells
Author(s) -
Anthony Kusnadi,
Ciro Ramírez-Suástegui,
Vicente Fajardo,
Serena Chee,
Benjamin J. Meckiff,
Hayley Simon,
Emanuela Pelosi,
Grégory Seumois,
Ferhat Ay,
Pandurangan Vijayanand,
Christian H. Ottensmeier
Publication year - 2021
Publication title -
science immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 8.83
H-Index - 51
ISSN - 2470-9468
DOI - 10.1126/sciimmunol.abe4782
Subject(s) - covid-19 , virology , sars virus , cd8 , medicine , immunology , biology , pathology , outbreak , immune system , disease , infectious disease (medical specialty)
Fewer SARS-CoV-2-reactive memory CD8 + T cells with ‘exhaustion’ features are present in COVID-19 patients with severe vs. mild disease.
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