Open AccessIL-23–producing IL-10Rα–deficient gut macrophages elicit an IL-22–driven proinflammatory epithelial cell response
Author(s) -
Biana Bernshtein,
Caterina Curato,
Μαριάννα Ιωάννου,
Christoph A. Thaiss,
Mor Gross-Vered,
Masha Kolesnikov,
Qian Wang,
Eyal David,
Louise ChappellMaor,
Alon Harmelin,
Eran Elinav,
Paresh Thakker,
Venizelos Papayannopoulos,
Steffen Jung
Publication year - 2019
Publication title -
science immunology
Language(s) - German
Resource type - Journals
SCImago Journal Rank - 8.83
H-Index - 51
ISSN - 2470-9468
DOI - 10.1126/sciimmunol.aau6571
Subject(s) - proinflammatory cytokine , immunology , biology , inflammation , interleukin 23 , microbiology and biotechnology , interleukin 17
Proinflammatory IL-10R–deficient colonic macrophages trigger defined T cell and epithelial responses causing colitis.
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