Mutation of a bHLH transcription factor allowed almond domestication
Author(s) -
Raquel SánchezPérez,
Stefano Pavan,
Rosa Mazzeo,
Claudiu MOLDOVAN,
Riccardo Aiese Cigliano,
Jorge Del Cueto,
Francesca Ricciardi,
Concetta Lotti,
Luigi M. Ricciardi,
F. Dicenta,
Rosa L. LópezMarqués,
Birger Lindberg Møller
Publication year - 2019
Publication title -
science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 12.556
H-Index - 1186
eISSN - 1095-9203
pISSN - 0036-8075
DOI - 10.1126/science.aav8197
Subject(s) - domestication , transcription factor , genetics , mutation , biology , gene
How to make almonds palatable The domesticated almond tree has been feeding humans for millennia. Derivation from the wild, bitter, and toxic almond required loss of the cyanogenic diglucoside amygdalin. Sánchez-Pérezet al. sequenced the almond genome and analyzed the genomic region responsible for this shift. The key change turned out to be a point mutation in a transcription factor that regulates production of P450 monooxygenases in the biosynthetic pathway for the toxic compound.Science , this issue p.1095
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom