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The complexity of maize domestication Maize originated in what is now central Mexico about 9000 years ago and spread throughout the Americas before European contact. Kistleret al. applied genomic analysis to ancient and extant South American maize lineages to investigate the genetic changes that accompanied domestication (see the Perspective by Zeder). The origin of modern maize cultivars likely involved a “semidomesticated” lineage that moved out of Mexico. Later improvements then occurred among multiple South American populations, including those in southwestern Amazonia.Science , this issue p.1309 ; see also p.1246

Multiproxy evidence highlights a complex evolutionary legacy of maize in South America