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Toward a targeted treatment for addiction
Author(s) -
Meaghan C. Creed
Publication year - 2017
Publication title -
science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 12.556
H-Index - 1186
eISSN - 1095-9203
pISSN - 0036-8075
DOI - 10.1126/science.aao1197
Subject(s) - addiction , neuroscience , deep brain stimulation , stimulation , synaptic plasticity , neuroplasticity , brain stimulation , psychology , chemistry , pharmacology , biology , medicine , biochemistry , receptor , disease , parkinson's disease
A major challenge in treating many neuropsychiatric disorders is that diagnoses are regularly based on behavior rather than on biomarkers, as well as the fact that such conditions are often not associated with gross structural brain changes. Addiction is one example of a disorder defined by pathological behavior (drug seeking despite harmful consequences) in which there is no significant loss of neurons and for which there is no cure.

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