An anatomic transcriptional atlas of human glioblastoma | Zendy

Ralph B. Puchalski | Zendy; Nameeta Shah | Zendy; Jeremy A. Miller | Zendy; Rachel Dalley | Zendy; Steve R. Nomura | Zendy; Jae-Guen Yoon | Zendy; Kimberly A. Smith | Zendy; Michael Lankerovich | Zendy; Darren Bertagnolli | Zendy; Kris Bickley | Zendy; Andrew F. Boe | Zendy; Krissy Brouner | Zendy; Stephanie Butler | Zendy; Shiella Caldejon | Zendy; Mike Chapin | Zendy; Suvro Datta | Zendy; Nick Dee | Zendy; Tsega Desta | Zendy; Tim Dolbeare | Zendy; Nadezhda Dotson | Zendy; Amanda Ebbert | Zendy; David Feng | Zendy; Xueli Feng | Zendy; Michael Fisher | Zendy; Garrett Gee | Zendy; Jeff Goldy | Zendy; Lindsey Gourley | Zendy; Benjamin W. Gregor | Zendy; Guangyu Gu | Zendy; Nika Hejazinia | Zendy; John G. Hohmann | Zendy; Parvinder Hothi | Zendy; Robert Howard | Zendy; Kevin Joines | Zendy; Ali Kriedberg | Zendy; Leonard Kuan | Zendy; Chris Lau | Zendy; Felix Lee | Zendy; Hwahyung Lee | Zendy; Tracy Lemon | Zendy; Fuhui Long | Zendy; Naveed Mastan | Zendy; Erika Mott | Zendy; Chantal Murthy | Zendy; Kiet Ngo | Zendy; Eric N. Olson | Zendy; Melissa Reding | Zendy; Zack L. Riley | Zendy; David Rosen | Zendy; David Sandman | Zendy; Nadiya V. Shapovalova | Zendy; Clifford R. Slaughterbeck | Zendy; Andrew Sodt | Zendy; Graham Stockdale | Zendy; Aaron Szafer | Zendy; Wayne Wakeman | Zendy; Paul Wohnoutka | Zendy; Steven J. White | Zendy; D. C. B. Marsh | Zendy; Robert Rostomily | Zendy; Lydia Ng | Zendy; Chinh Dang | Zendy; Allan R. Jones | Zendy; Bart P. Keogh | Zendy; Haley Gittleman | Zendy; Jill S. BarnholtzSloan | Zendy; Patrick J. Cimino | Zendy; Megha Uppin | Zendy; C. Dirk Keene | Zendy; Farrokh Farrokhi | Zendy; Justin D. Lathia | Zendy; Michael E. Berens | Zendy; Antonio Iavarone | Zendy; Amy Bernard | Zendy; Ed S. Lein | Zendy; John W. Phillips | Zendy; Steven Rostad | Zendy; Charles Cobbs | Zendy; Michael Hawrylycz | Zendy; Greg Foltz | Zendy

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An anatomic transcriptional atlas of human glioblastoma

Author(s) -

Ralph B. Puchalski,

Nameeta Shah,

Jeremy A. Miller,

Rachel Dalley,

Steve R. Nomura,

Jae-Guen Yoon,

Kimberly A. Smith,

Michael Lankerovich,

Darren Bertagnolli,

Kris Bickley,

Andrew F. Boe,

Krissy Brouner,

Stephanie Butler,

Shiella Caldejon,

Mike Chapin,

Suvro Datta,

Nick Dee,

Tsega Desta,

Tim Dolbeare,

Nadezhda Dotson,

Amanda Ebbert,

David Feng,

Xueli Feng,

Michael Fisher,

Garrett Gee,

Jeff Goldy,

Lindsey Gourley,

Benjamin W. Gregor,

Guangyu Gu,

Nika Hejazinia,

John G. Hohmann,

Parvinder Hothi,

Robert Howard,

Kevin Joines,

Ali Kriedberg,

Leonard Kuan,

Chris Lau,

Felix Lee,

Hwahyung Lee,

Tracy Lemon,

Fuhui Long,

Naveed Mastan,

Erika Mott,

Chantal Murthy,

Kiet Ngo,

Eric N. Olson,

Melissa Reding,

Zack L. Riley,

David Rosen,

David Sandman,

Nadiya V. Shapovalova,

Clifford R. Slaughterbeck,

Andrew Sodt,

Graham Stockdale,

Aaron Szafer,

Wayne Wakeman,

Paul Wohnoutka,

Steven J. White,

D. C. B. Marsh,

Robert Rostomily,

Lydia Ng,

Chinh Dang,

Allan R. Jones,

Bart P. Keogh,

Haley Gittleman,

Jill S. BarnholtzSloan,

Patrick J. Cimino,

Megha Uppin,

C. Dirk Keene,

Farrokh Farrokhi,

Justin D. Lathia,

Michael E. Berens,

Antonio Iavarone,

Amy Bernard,

Ed S. Lein,

John W. Phillips,

Steven Rostad,

Charles Cobbs,

Michael Hawrylycz,

Greg Foltz

Publication year - 2018

Publication title -

science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 12.556

H-Index - 1186

eISSN - 1095-9203

pISSN - 0036-8075

DOI - 10.1126/science.aaf2666

Subject(s) - glioblastoma , atlas (anatomy) , brain tumor , biology , brain atlas , pathogenesis , pathology , human protein atlas , gene , computational biology , bioinformatics , cancer research , neuroscience , medicine , protein expression , genetics , anatomy

Anatomically correct tumor genomics Glioblastoma is the most lethal form of human brain cancer. The genomic alterations and gene expression profiles characterizing this tumor type have been widely studied. Puchalskiet al. created the Ivy Glioblastoma Atlas, a freely available online resource for the research community. The atlas, a collaborative effort between bioinformaticians and pathologists, maps molecular features of glioblastomas, such as transcriptional signatures, to histologically defined anatomical regions of the tumors. The relationships identified in this atlas, in conjunction with associated databases of clinical and genomic information, could provide new insights into the pathogenesis, diagnosis, and treatment of glioblastoma.Science , this issue p.660

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