Response to Comment on “Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism” | Zendy

Fei Li | Zendy; Jian Liu | Zendy; Yi Zheng | Zendy; R. Michael Garavito | Zendy; Shelagh FergusonMiller | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Response to Comment on “Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism”

Author(s) -

Fei Li,

Jian Liu,

Yi Zheng,

R. Michael Garavito,

Shelagh FergusonMiller

Publication year - 2015

Publication title -

science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 12.556

H-Index - 1186

eISSN - 1095-9203

pISSN - 0036-8075

DOI - 10.1126/science.aab2595

Subject(s) - translocator protein , mutant , rhodobacter sphaeroides , polyethylene glycol , porphyrin , crystallography , chemistry , polymorphism (computer science) , biophysics , biology , biochemistry , gene , genotype , photosynthesis , neuroinflammation , immunology , inflammation

Wang comments that the diffraction data for the structure of the A139T mutant of translocator protein TSPO from Rhodobacter sphaeroides should be used to 1.65 instead of 1.8 angstroms and that the density interpreted as porphyrin and monoolein is better fitted as polyethylene glycol. Although different practices of data processing exist, in this case they do not substantially influence the final map. Additional data are presented supporting the fit of a porphyrin and monooleins.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research