Response to Comment on “Restoring Voluntary Control of Locomotion After Paralyzing Spinal Cord Injury” | Zendy

Grégoire Courtine | Zendy; Janine Heutschi | Zendy; Rubia van den Brand | Zendy

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Response to Comment on “Restoring Voluntary Control of Locomotion After Paralyzing Spinal Cord Injury”

Author(s) -

Grégoire Courtine,

Janine Heutschi,

Rubia van den Brand

Publication year - 2012

Publication title -

science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 12.556

H-Index - 1186

eISSN - 1095-9203

pISSN - 0036-8075

DOI - 10.1126/science.1226274

Subject(s) - spinal cord injury , spinal cord , physical medicine and rehabilitation , turnover , control (management) , neuroscience , medicine , psychology , computer science , economics , management , artificial intelligence

Sławińskaet al . questioned the involvement of supraspinal centers in restoring locomotion after multisystem neuroprosthetic training in rats with paralyzing spinal cord injury. Here, we clarify misconceptions and present additional results illustrating the robust influence of brain input on electrochemically enabled spinal circuitries. We reassert that our intervention reestablished supraspinal control over hindlimb locomotion in paralyzed rats.

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