Tackling Human Fungal Infections | Zendy

Gordon D. Brown | Zendy; David W. Denning | Zendy; Stuart M. Levitz | Zendy

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Tackling Human Fungal Infections

Author(s) -

Gordon D. Brown,

David W. Denning,

Stuart M. Levitz

Publication year - 2012

Publication title -

science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 12.556

H-Index - 1186

eISSN - 1095-9203

pISSN - 0036-8075

DOI - 10.1126/science.1222236

Subject(s) - malaria , tuberculosis , epidemiology , disease , mortality rate , infectious disease (medical specialty) , incidence (geometry) , fungal disease , psychological intervention , medicine , environmental health , intensive care medicine , immunology , pathology , dermatology , surgery , physics , psychiatry , optics

Fungi infect billions of people every year, yet their contribution to the global burden of disease is largely unrecognized. Most are “relatively” minor infections, but millions contract diseases that kill at least as many people as tuberculosis or malaria. Although true mortality rates are unknown because of a lack of good epidemiological data, the incidence of invasive fungal infections is rising as a result of modern medical interventions and immunosuppressive diseases, such as AIDS. Despite the high mortality rates of invasive fungal infections, they remain understudied and underdiagnosed as compared with other infectious diseases. What can be done to remedy this unfortunate situation?

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