The Automation of Science | Zendy

Ross D. King | Zendy; Jem J. Rowland | Zendy; Stephen G. Oliver | Zendy; Michael J. Young | Zendy; Wayne Aubrey | Zendy; Emma Byrne | Zendy; Maria Liakata | Zendy; Magdalena Markham | Zendy; Pınar Pir | Zendy; Larisa Soldatova | Zendy; Andrew C. Sparkes | Zendy; Kenneth E. Whelan | Zendy; Amanda Clare | Zendy

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The Automation of Science

Author(s) -

Ross D. King,

Jem J. Rowland,

Stephen G. Oliver,

Michael J. Young,

Wayne Aubrey,

Emma Byrne,

Maria Liakata,

Magdalena Markham,

Pınar Pir,

Larisa Soldatova,

Andrew C. Sparkes,

Kenneth E. Whelan,

Amanda Clare

Publication year - 2009

Publication title -

science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 12.556

H-Index - 1186

eISSN - 1095-9203

pISSN - 0036-8075

DOI - 10.1126/science.1165620

Subject(s) - automation , computer science , ontology , artificial intelligence , data science , epistemology , philosophy , engineering , mechanical engineering

The basis of science is the hypothetico-deductive method and the recording of experiments in sufficient detail to enable reproducibility. We report the development of Robot Scientist "Adam," which advances the automation of both. Adam has autonomously generated functional genomics hypotheses about the yeast Saccharomyces cerevisiae and experimentally tested these hypotheses by using laboratory automation. We have confirmed Adam's conclusions through manual experiments. To describe Adam's research, we have developed an ontology and logical language. The resulting formalization involves over 10,000 different research units in a nested treelike structure, 10 levels deep, that relates the 6.6 million biomass measurements to their logical description. This formalization describes how a machine contributed to scientific knowledge.

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