Serotonin Modulates Behavioral Reactions to Unfairness | Zendy

Molly J. Crockett | Zendy; Luke Clark | Zendy; Golnaz Tabibnia | Zendy; Matthew D. Lieberman | Zendy; Trevor W. Robbins | Zendy

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Serotonin Modulates Behavioral Reactions to Unfairness

Author(s) -

Molly J. Crockett,

Luke Clark,

Golnaz Tabibnia,

Matthew D. Lieberman,

Trevor W. Robbins

Publication year - 2008

Publication title -

science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 12.556

H-Index - 1186

eISSN - 1095-9203

pISSN - 0036-8075

DOI - 10.1126/science.1155577

Subject(s) - ultimatum game , impulsivity , serotonin , mood , psychology , social psychology , developmental psychology , medicine , receptor

Serotonin (5-HT) has long been implicated in social behavior and impulsivity, but the mechanisms through which it modulates self-control remain unclear. We observed the effects of manipulating 5-HT function on behavior in the ultimatum game, where players must decide whether to accept or reject fair or unfair monetary offers from another player. Participants with depleted 5-HT levels rejected a greater proportion of unfair offers, but not fair offers, without showing changes in mood, fairness judgment, basic reward processing, or response inhibition. Our results suggest that 5-HT plays a critical role in regulating emotion during social decision-making

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