Open AccessComment on "Magnetic Resonance Spectroscopy Identifies Neural Progenitor Cells in the Live Human Brain"
Author(s) -
Jeffrey C. Hoch,
Mark W. Maciejewski,
Michael R. Gryk
Publication year - 2008
Publication title -
science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 12.556
H-Index - 1186
eISSN - 1095-9203
pISSN - 0036-8075
DOI - 10.1126/science.1153058
Subject(s) - nuclear magnetic resonance , neural stem cell , spectroscopy , progenitor , progenitor cell , nuclear magnetic resonance spectroscopy , biology , chemistry , physics , microbiology and biotechnology , stem cell , quantum mechanics
Manganaset al . (Reports, 9 November 2007, p. 980) used nuclear magnetic resonance spectroscopy to identify a biomarker of neural progenitor cells. However, their analysis relies on spectral processing methods that are known to be problematic. Absent detection using alternate methods of spectrum analysis or controls to quantify the false discovery rate, their conclusions may be premature.