Nuclear Gene Indicates Coat-Color Polymorphism in Mammoths
Author(s) -
Holger Römpler,
Nadin Rohland,
Carles LaluezaFox,
Eske Willerslev,
Т. В. Кузнецова,
Gernot Rabeder,
Jaume Bertranpetit,
Torsten Schöneberg,
Michael Hofreiter
Publication year - 2006
Publication title -
science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 12.556
H-Index - 1186
eISSN - 1095-9203
pISSN - 0036-8075
DOI - 10.1126/science.1128994
Subject(s) - coat , biology , melanocortin 1 receptor , genetics , allele , gene , polymorphism (computer science) , evolutionary biology , ecology
By amplifying the melanocortin type 1 receptor from the woolly mammoth, we can report the complete nucleotide sequence of a nuclear-encoded gene from an extinct species. We found two alleles and show that one allele produces a functional protein whereas the other one encodes a protein with strongly reduced activity. This finding suggests that mammoths may have been polymorphic in coat color, with both dark- and light-haired individuals co-occurring.
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