Open AccessResponse to Comment on "Role of NMDA Receptor Subtypes in Governing the Direction of Hippocampal Synaptic Plasticity"
Author(s) -
Tak Pan Wong,
Lidong Liu,
Morgan Sheng,
Yu Tian Wang
Publication year - 2004
Publication title -
science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 12.556
H-Index - 1186
eISSN - 1095-9203
pISSN - 0036-8075
DOI - 10.1126/science.1102399
Subject(s) - nmda receptor , neuroscience , hippocampal formation , synaptic plasticity , plasticity , biology , receptor , physics , biochemistry , thermodynamics
As a result of the differential (intrasynaptic versus extrasynaptic) localization and agonist affinity of NR2A-containing and NR2B-containing N -methyl-d-aspartate receptors (NMDARs), Rusakov et al . ([ 1 ][1]) propose that the production of long-term potentiation (LTP) versus long-term depression (
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