Apoptosis--the Calcium Connection
Author(s) -
Nicolas Demaurex,
Clark Distelhorst
Publication year - 2003
Publication title -
science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 12.556
H-Index - 1186
eISSN - 1095-9203
pISSN - 0036-8075
DOI - 10.1126/science.1083628
Subject(s) - calcium , connection (principal bundle) , apoptosis , ionic bonding , chemistry , self healing hydrogels , polysaccharide , microbiology and biotechnology , biophysics , biochemistry , ion , biology , engineering , polymer chemistry , organic chemistry , structural engineering
Calcium ions are crucial to many cellular processes including apoptosis. In their Perspective, Demaurex and Distelhorst explain new work that shows how calcium ions flowing between the endoplasmic reticulum (ER) and mitochondria regulate programmed cell death, highlighting the ER as a new gateway to apoptosis ( Scorrano et al.).
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