Therapeutic inhibition of the SRC-kinase HCK facilitates T cell tumor infiltration and improves response to immunotherapy
Author(s) -
Ashleigh R. Poh,
Christopher G. Love,
David Chisanga,
James H. Steer,
David Baloyan,
Michaël Chopin,
Stephen L. Nutt,
Jai Rautela,
Nicholas D. Huntington,
Nima Etemadi,
Megan A. O’Brien,
Ryan O’Keefe,
Lesley G. Ellies,
Christophe Macri,
Justine D. Mintern,
Lachlan Whitehead,
Gangadhara Gangadhara,
Louis Boon,
Ashwini L. Chand,
Clifford A. Lowell,
Wei Shi,
Fiona J. Pixley,
Matthias Ernst
Publication year - 2022
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abl7882
Subject(s) - immunotherapy , cancer research , tumor microenvironment , immunogenic cell death , cancer immunotherapy , cd8 , t cell , medicine , immune system , dendritic cell , immunology , biology
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