Open AccessSingle-cell transcriptome of early hematopoiesis guides arterial endothelial-enhanced functional T cell generation from human PSCs
Author(s) -
Jun Shen,
Yingxi Xu,
Shuo Zhang,
Siqi Lyu,
Yingying Huo,
Yaoyao Zhu,
Kejing Tang,
Junli Mou,
Xinjie Li,
Dixie L. Hoyle,
Min Wang,
Jianxiang Wang,
Xin Li,
Zack Z. Wang,
Tao Cheng
Publication year - 2021
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abi9787
Subject(s) - biology , haematopoiesis , microbiology and biotechnology , induced pluripotent stem cell , transcriptome , stem cell , cellular differentiation , progenitor cell , endothelial stem cell , immunology , in vitro , gene expression , gene , genetics , embryonic stem cell
Hypoxia enhances hematopoiesis with functional T cell potential from human pluripotent stem cells via arterial priming.