Single-cell transcriptome of early hematopoiesis guides arterial endothelial-enhanced functional T cell generation from human PSCs | Zendy

Jun Shen | Zendy; Yingxi Xu | Zendy; Shuo Zhang | Zendy; Shuzhen Lyu | Zendy; Yingying Huo | Zendy; Yaoyao Zhu | Zendy; Kejing Tang | Zendy; Junli Mou | Zendy; Xinjie Li | Zendy; Dixie L. Hoyle | Zendy; Min Wang | Zendy; Jianxiang Wang | Zendy; Xin Li | Zendy; Zack Z. Wang | Zendy; Tao Cheng | Zendy

Open Access

Single-cell transcriptome of early hematopoiesis guides arterial endothelial-enhanced functional T cell generation from human PSCs

Author(s) -

Jun Shen,

Yingxi Xu,

Shuo Zhang,

Shuzhen Lyu,

Yingying Huo,

Yaoyao Zhu,

Kejing Tang,

Junli Mou,

Xinjie Li,

Dixie L. Hoyle,

Min Wang,

Jianxiang Wang,

Xin Li,

Zack Z. Wang,

Tao Cheng

Publication year - 2021

Publication title -

science advances

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.928

H-Index - 146

ISSN - 2375-2548

DOI - 10.1126/sciadv.abi9787

Subject(s) - biology , haematopoiesis , microbiology and biotechnology , induced pluripotent stem cell , transcriptome , stem cell , cellular differentiation , progenitor cell , endothelial stem cell , immunology , in vitro , gene expression , gene , genetics , embryonic stem cell

Hypoxia enhances hematopoiesis with functional T cell potential from human pluripotent stem cells via arterial priming.

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