Open AccessCristae-dependent quality control of the mitochondrial genome
Author(s) -
Christopher Jakubke,
Rodaria Roussou,
Andreas Maiser,
Christina Schug,
Felix Thoma,
David M. Bunk,
David Hörl,
Heinrich Leonhardt,
Peter Walter,
Till Klecker,
Christof Osman
Publication year - 2021
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abi8886
Subject(s) - mitochondrial dna , biology , mitochondrion , mitochondrial fission , saccharomyces cerevisiae , genetics , genome , microbiology and biotechnology , yeast , gene , computational biology
Cristae limit diffusion of mtDNA-encoded proteins and facilitate clearance of mutant mtDNA in a fission-independent manner.